Body Size, Weight Change, and Risk of Colon Cancer

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Body size, weight change, and risk of colon cancer.

BACKGROUND Epidemiologic studies have consistently reported positive associations between obesity and colon cancer risk for men, but the evidence is less consistent for women. Few studies have investigated effects of weight change on colon cancer risk. METHODS Using the Melbourne Collaborative Cohort Study, which recruited men and women mostly in 40 to 69 years of age, we investigated associa...

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Body Size and Composition and Colon Cancer Risk in Men

Background: Several studies of male colon cancer have found positive associations with body size and composition. It is uncertain whether this relationship is due to non-adipose mass, adipose mass, distribution of adipose mass such as central adiposity, or all three. Methods: In a prospective cohort study of men aged 27–75 at recruitment in 1990–1994, body measurements were taken by interviewer...

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Body size and composition and colon cancer risk in women.

Studies of colon cancer risk in males have reported strong positive associations with obesity, particularly with central adiposity. The association has been weaker and less consistent for women. In a prospective cohort study of women, body measurements were taken directly; fat mass and fat-free mass being estimated by bioelectrical impedance analysis and central adiposity by waist circumference...

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A prospective study of body mass index, weight change, and risk of cancer in the proximal and distal colon.

BACKGROUND Body mass index (BMI) is an established risk factor for colon cancer, but risks may differ between genders and colon subsites. Moreover, whether weight change influences risk is not yet clarified. We investigated these issues in a large, Norwegian, population-based cohort study. METHODS Participants' weight was measured at examinations up to three times between 1974 and 1988. Hazar...

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Weight change and risk of endometrial cancer.

BACKGROUND Obesity is an established risk factor for endometrial cancer. Less well understood is the role of weight gain and weight change in determining risk. METHODS We analysed data from a population-based case-control study to evaluate the associations of body mass index (BMI), weight gain, and weight cycling with risk of endometrial cancer. Cases (n=740) under age 80 with a new diagnosis...

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ژورنال

عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention

سال: 2010

ISSN: 1055-9965,1538-7755

DOI: 10.1158/1055-9965.epi-10-0543